Global
CN

LKtime Biotech (Changchun)

R&D Center Drug Substance (DS) production Drug Product (DP) production Quality Analysis and Control Customized CDMO Service

Blow-Fill-Seal Machine Integrated Production Line


The Blow-Fill-Seal Machine (BFS) employs specialized aseptic packaging technology to perform continuous operations. It automatically converts medical-grade polyethylene (PE) or polypropylene (PP) granules into containers, seamlessly integrating blow molding, filling, and sealing processes within a single device. Operating under sterile conditions, the BFS machine executes the entire sequence - blowing the plastic container, filling it with product, and hermetically sealing it - in a rapid, continuous cycle. This integrated approach consolidates multiple manufacturing steps into one system, ensuring product safety and minimizing contamination risks.

 

The equipment offers significant advantages, including low production and management costs, excellent aseptic stability, high intrinsic product quality, and minimal cross-contamination risks. It is widely applicable in the production of terminally sterilized products and aseptic products utilizing plastic packaging.

 

This production line delivers a stable output of 18,000 bottles/hour, accommodating a broad range of specifications from 0.1 mL to 20 mL. It integrates a highly automated control and management system featuring audit trail, access control, data integrity, electronic records, and operational traceability, ensuring full compliance with regulatory requirements.


  • [Filling Volume] 0.1 mL ~ 20 mL
  • [Production Capacity] 18,000 bottles/hour
  • [Standard] cGMP Compliance
  • Main Equipment
  • Blow-Fill-Seal Machine